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UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

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Summary: Colorectal cancer (CRC) is associated with metabolic and redox perturbation. The mitochondrial transporter uncoupling protein 2 (UCP2) controls cell proliferation in vitro through the modulation of cellular metabolism. but the underlying mechanism in tumors in vivo remains unexplored. Using murine intestinal cancer models and CRC patient samples. https://www.roneverhart.com/NeOn-Zero-Lefty-M390-BLADE-TITANIUM-HANDLE-MRBS-p11472/
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