High Glucose links to dysfunctions of glucose uptake and catabolism and induces significant oxidative worry, dysfunction of endothelial cells. Large hypertension brings about cardiac and vascular injuries. Central weight problems is related to maldistribution of totally free fatty acid, overproduction of inflammatory molecules, and leptin resistance [21]. Cardiovascular threat things https://www.directivepublications.org/journal-of-cardiovascular-diseases/